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Ingredient · INCI listed

Papain

An enzyme from papaya that exfoliates by digesting surface proteins — a gentler, acid-free route to smoother texture, though less consistent and harder to stabilize than acids.

Data summary
Products containing
36
Most common in
12 products
cleansers
Typical pairing
Salicylic Acid (BHA)
View 36 products with papain →
In the catalog

Papain by the numbers.

Papain appears in 36 products across the DermFND catalog, most often in cleansers (12 products) but also across exfoliants and treatments. Formulations carrying it score 72/100 on average (above the catalog norm); the strongest is By Wishtrend Green Tea & Enzyme Powder Wash at 86/100.

Of those, 3 products score 80 or higher in our analysis. It co-occurs most with Salicylic Acid (9 shared formulas) and Lactic Acid (8 shared formulas). The median price of a papain product here is $46.

Where it shows up

papain across the catalog.

36 products with papain

#1 By Wishtrend Green Tea & Enzyme Powder Wash 80g frosted jar with sifter cap
By Wishtrend
Green Tea & Enzyme Powder Wash
K-Beauty Enzyme Pick
86/100 $24.00
#2 ZO Skin Health Brightalive Skin Brightener pump bottle
ZO Skin Health
Brightalive Skin Brightener
Hydroquinone-Free Brightening
81/100 $117.00
#3 Dermalogica Daily Microfoliant powder exfoliant in a cylindrical shaker bottle
Dermalogica
Daily Microfoliant
Cult Classic Exfoliant
80/100 $69.00
#4 iS Clinical Warming Honey Cleanser in white tube packaging
iS Clinical
Warming Honey Cleanser
Spa-Ritual Cleanser
79/100 $52.00
#5 Youth to the People Yerba Mate Resurfacing Energy Facial squeeze tube
Youth to the People
Yerba Mate Resurfacing Energy Facial
Triple-Action Exfoliator
79/100 $48.00
#6 Kosas Good Body Skin AHA + Enzyme Exfoliating Body Wash in a squeeze bottle
Kosas
Good Body Skin AHA + Enzyme Exfoliating Body Wash
Body Texture Transformer
78/100 $22.00
#7 Anua Rice Enzyme Brightening Cleansing Powder 40g jar with rice line branding
Anua
Rice Enzyme Brightening Cleansing Powder
K-Beauty Enzyme Exfoliant
78/100 $20.00
#8 Good Molecules Pineapple Exfoliating Powder in a plastic shaker bottle with white label
Good Molecules
Pineapple Exfoliating Powder
Sensitive Skin Exfoliator
78/100 $16.00
#9 SkinBetter Science Detoxifying Scrub Mask jar
SkinBetter Science
Detoxifying Scrub Mask
Derm Office Multi-Mode Exfoliant
78/100 $75.00
#10 Banila Co Clean It Zero Cleansing Balm Purifying in green tub
Banila Co
Clean It Zero Cleansing Balm Purifying
K-Beauty Cult Favorite
78/100 $19.00
#11 COSRX Low pH Goodnight Soft Peeling Gel 120ml tube with minimalist white packaging
COSRX
Low pH Goodnight Soft Peeling Gel
Sensitive Skin MVP
77/100 $16.00
#12 Dermalogica Daily Superfoliant in a dark grey cylindrical shaker bottle
Dermalogica
Daily Superfoliant
Urban Skin Defense Exfoliant
77/100 $69.00
#13 Elemis Dynamic Resurfacing Facial Wash enzyme gel cleanser in a white tube
Elemis
Dynamic Resurfacing Facial Wash
Spa-Grade Daily Resurfacer
76/100 $55.00
#14 Numbuzin No. 3 Rice Enzyme Skin Softening Cleansing Foam tube with rice grain-inspired
Numbuzin
No. 3 Rice Enzyme Skin Softening Cleansing Foam
Multi-Tasking Enzyme Cleanser
76/100 $13.00
#15 DefenAge Clinical Power Trio set of three products in box
DefenAge
Clinical Power Trio
Derm Office Staple
76/100 $365.00
#16 Sand & Sky Enzyme Polish & Exfoliant 60g jar — Australian rice and papain powder-to-foam exfoliator
Sand & Sky
Enzyme Polish & Exfoliant
Australian Enzyme Brightener
74/100 $39.00
#17
Augustinus
Augustinus Bader
The Essence
Luxury Exfoliating Essence
74/100 $145.00
#18 Glow Recipe Papaya Sorbet Enzyme Cleansing Balm in coral glass jar
Glow Recipe
Papaya Sorbet Enzyme Cleansing Balm
Enzyme-Powered First Cleanse
72/100 $32.00
#19 White tube of Dr.G Brightening Peeling Gel Korean skincare exfoliant
Dr.G
Brightening Peeling Gel
K-Beauty Weekly Glow Ritual
72/100 $25.00
#20 Laneige Water Bank Blue Hyaluronic Cleansing Foam in a blue and white squeeze tube
Laneige
Water Bank Blue Hyaluronic Cleansing Foam
K-Beauty Hydrating Cleanser
71/100 $25.00
#21 SKIN1004 Poremizing Deep Cleansing Foam 125ml tube with green and white packaging
SKIN1004
Poremizing Deep Cleansing Foam
K-Beauty Oily-Skin Foam
71/100 $14.00
#22 ZO Skin Health Rozatrol 1.7 oz airless pump bottle for rosacea and red sensitized skin
ZO Skin Health
Rozatrol Treatment for Red Sensitized Skin
Rosacea Specialty Pick
71/100 $105.00
#23 Herbivore Botanicals Blue Tansy Resurfacing Clarity Face Mask in clear glass jar showing deep
Herbivore Botanicals
Blue Tansy Resurfacing Clarity Face Mask
Cult Sephora Blue Tansy Mask
71/100 $58.00
#24 Revolution Skincare 2% Salicylic Acid and Fruit Enzymes Serum 60ml glass dropper bottle
Revolution Skincare
2% Salicylic Acid & Fruit Enzymes Serum
Budget Blackhead Buster
71/100 $10.00
#25 CNP Laboratory Anti-Pore Black Head Clear Kit two-step bottles in box
CNP Laboratory
Anti-Pore Black Head Clear Kit
K-Beauty Pore Ritual
71/100 $22.00
#26 Revision Skincare Papain Enzyme Cleanser gel cleanser bottle
Revision Skincare
Papain Enzyme Cleanser
Daily Enzyme Exfoliation Made Simple
70/100 $47.00
#27 Kate Somerville ExfoliKate Cleanser Daily Foaming Wash tube
Kate Somerville
ExfoliKate Cleanser Daily Foaming Wash
Daily Glow Booster
69/100 $46.00
#28 Sunday Riley Tidal Brightening Enzyme Water Cream blue gel in glass jar
Sunday Riley
Tidal Brightening Enzyme Water Cream
Lightweight Glow Getter
69/100 $65.00
#29 DefenAge 2-Minute Reveal Masque white pump tube
DefenAge
2-Minute Reveal Masque
Derm Office Staple
69/100 $88.00
#30 Kate Somerville ExfoliKate Intensive Exfoliating Treatment green tube
Kate Somerville
ExfoliKate Intensive Exfoliating Treatment
Cult Classic Exfoliant
65/100 $85.00
#31 Caudalie Instant Detox Mask tube
Caudalie
Instant Detox Mask
Gentle Clay Mask
64/100 $39.00
#32 Exuviance Triple Microdermabrasion Face Polish tube with triple-action exfoliating treatment
Exuviance
Triple Microdermabrasion Face Polish
Triple-Action Resurfacing Treatment
62/100 $78.00
#33 Lancôme Clarifique Dual Essence in glass bottle showing bi-phase liquid formula
Lancôme
Clarifique Dual Essence
Enzyme Science Innovator
60/100 $88.00
#34 Holika Holika Smooth Egg Skin Peeling Gel 140ml tube
Holika Holika
Smooth Egg Skin Peeling Gel
K-Beauty Nostalgia Pick
60/100 $14.00
#35 Kopari California Glow Enzyme Face Scrub in a small tube with tropical-inspired packaging
Kopari
California Glow Enzyme Face Scrub
California Clean Glow-Getter
57/100 $30.00
#36 Lancôme Lait Galatéis Douceur Gentle Softening Cleansing Fluid in pump bottle
Lancôme
Lait Galatéis Douceur Gentle Softening Cleansing Fluid
French Pharmacy Classic
56/100 $48.50

Often paired with.

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